Caffeine Anhydrous
The most-studied ergogenic aid for both performance and focus. Unlike coffee, the dose is precisely controllable.
Typical dose
3–6mg per kg body weight (e.g., 200–400mg at 70kg)
Timing
30–60 min before training. Avoid late afternoon — it compromises sleep.
Monthly cost (approx.)
~$2
Primary goals
performance · fatloss
Scientific Evidence
Papers Forgestack cites for Caffeine Anhydrous recommendations. Each link goes to PubMed or an official society source.
- ISSN PositionTier 1
Guest et al. 2021 · PubMed / Source
- Meta-AnalysisTier 1
Grgic et al. 2020 · PubMed / Source
- ReviewTier 2
Spriet 2014 · PubMed / Source
- ReviewTier 3
Pickering & Kiely 2018 · PubMed / Source
- Safety EvidenceTier 1Safety
EFSA 2015 · PubMed / Source
Side Effects & Cautions
- common
Palpitations, anxiety, insomnia, elevated BP above 400mg/day
- frequent
Reduced sleep quality when taken late in the day
- rare
Headache and fatigue for several days when quitting abruptly
Consult a physician or pharmacist if in doubt. Forgestack does not provide medical advice.
Interactions
SSRIs / anxiety medications
May amplify anxiety side-effects.
Antihypertensive medication
Transient BP spikes can partially offset the medication.
Thyroid hormone medication
Coffee within 1 hour of levothyroxine can cut absorption by up to 50%.
Where to Buy
The links below are affiliate links. Your price does not change.
Whether this supplement should be your top priority depends on your goal and current stack.